Insulin-like growth factor-1 (IGF-1) is a compound produced using recombinant DNA technology. It serves as the main mediator for the growth-promoting actions of human growth hormone. Consequently, IGF-1 can encourage the development of bone, muscle, and internal organs. Its impact on skeletal muscle is also notably hyperplastic, meaning it leads to an increase in cell quantity. However, unlike human growth hormone, this substance has pronounced insulin-like properties. It can facilitate growth by enhancing the absorption of amino acids, glucose, and fatty acids, but it can also lower blood sugar levels so effectively that it might cause severe hypoglycemia if an excessively high dose is administered.
Among the various anabolic benefits IGF-1 can generate in the body are enhancing protein synthesis, improving nitrogen retention, and promoting the growth of additional muscle fibers. When there is an adequate supply of amino acids (protein), all these functions within the body can take place. Research has indicated that IGF-1 can aid in boosting collagen production and fostering cartilage regeneration in joints. Additionally, this hormone has been demonstrated to possess neuroprotective and promotive characteristics, primarily due to the presence of IGF-1 receptors in brain tissue. Studies suggest that supplementing with IGF-1 may help slow the progression of certain brain diseases and mitigate cognitive decline in some elderly individuals.
Regarding IGF-1 dosing, users have reported positive outcomes with doses ranging from 100 to 160 mcg per day. This total dosage is typically divided into several injections, most of which are likely administered following workouts.